Liquisolid tablets for dissolution enhancement of a hypolipidemic drug
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چکیده
منابع مشابه
Liquisolid Tablets for Dissolution Enhancement of a Hypolipidemic Drug
This investigation was aimed to improve the dissolution rate of the poorly soluble drug lovastatin, by formulating it as a liquisolid compact. Different liquisolid compacts were prepared using mathematical formulae to calculate the required quantities of powder and liquid ingredients to produce acceptably flowable and compressible admixture. Avicel PH 200, Cab-O-Sil, sodium starch glycolate and...
متن کاملEnhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
متن کاملEnhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
متن کاملLiquisolid Technique for Enhancement of Dissolution Properties of Fenofibrate
The in vitro dissolution property of slightly water soluble Fenofibrate (FN) was improved by exploring the potential of Liquisolid system (LS). The in vitro release pattern of LS compacts and directly compressed tablets were studied using USP-II apparatus. Different LS compacts were prepared using a mathematical model to calculate the required quantities of powder and liquid ingredients to prod...
متن کاملEnhancement of Dissolution Properties of Amlodipine Besylate Using Liquisolid Technique
The most promising method for enhancing solubility, therefore promoting the rate of dissolution is the formation of liquisolid compacts.[2]With Liquisolid technique as described by Spireas liquid formulations such as solutions or suspensions of poorly soluble drugs in a non-volatile liquid vehicle are converted into acceptably flowing and compressible powders, by simple physical blending with s...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2015
ISSN: 0250-474X
DOI: 10.4103/0250-474x.159618